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GPX5 is synthesized primarily by epididymal head epithelial cells and secreted into the epididymal cavity to compensate for a deficiency of antioxidant enzymes in immature sperm (Seligman et al., 2005)

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In the liver, although both increased FFA uptake and upregulated de novo lipogenesis contribute to the development of hepatic steatosis, accumulating evidence suggests that increased FFA uptake plays a predominant role in the development of fatty livers 1

TousoulisDPlastirasASiasosGOikonomouEVerveniotisAKokkouEet al