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The antitumor activity in vitro and in a xenograft mouse model in vivo was further enhanced when DECR1-directed siRNA, which induced selective DECR1 silencing, was combined with FIN56 [23]

Polchi A, Magini A, Mazuryk J, Tancini B, Gapiski J, Patkowski A et al (2016) Rapamycin loaded solid lipid nanoparticles as a new tool to deliver mTOR inhibitors: formulation and in vitro characterization

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There is an upward trend in gene expression from moderate illness to severe illness at each day post-onset, suggesting sustained up-regulation of genes functional in NETosis in severe illness

12 19 Alcohol Dehydrogenase ADH, a zinc-containing dimer enzyme located in the cytoplasm, is the most important enzyme in the metabolism of ethanol to acetaldehyde