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2.5 Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias

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Mechanism of action These agents cause direct relaxation of peripheral arterial smooth muscle and thereby significantly decrease peripheral resistance

If needed, ice or numbing options are available to improve comfort

Many people using Semaglutide report brain fog, which can make daily tasks harder

The products are injected intravenously