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Tackling a vitamin B12 deficiency early on is crucial to avoid these problems and maintain healthy teeth and gums

Its low side-effect profile is also reassuring, making it attractive to those looking for alternative healing options

Furthermore, the pharmacological inhibition of HDAC8 can effectively suppress p53 and p21 expressions and the phosphorylation of the cyclin-dependent kinase 2 (CDK2) induced by cisplatin to reduce the expression of pro-apoptotic genes, thus alleviating apoptosis and cell cycle arrest (Wang et al., 2024c)