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GSTP1 is generally not expressed in human hepatocytes (Sison-Young et al., 2015), however, expression is often up-regulated under stress conditions and in tumors (Tew and Townsend, 2012)

Building upon the observed shifts in hepatic glucose handling and systemic substrate utilization, we next examined how GPR146 deficiency influences energy expenditure, revealing striking sex-specific differences

They proposed a microfluidic platform constituted of three regions in which patient-derived B-ALL cells from different subtypes, together with primary commercial HUVECs, mesenchymal stem cells (MSC) and osteoblasts, were seeded for mimicking the human cytological and histological complexity of bone marrow ( Figures 5A-C )

In cells, H 2 O 2 serves as a critical signaling molecule capable of conveying redox rhythm signals to targets both in close proximity and at a distance

Chen W, Chen M, Zang Q, Wang L, Tang F, Han Y, Yang C, Deng L, Liu Y-N

Recent work has identified the endocannabinoid system (ECS) as a key mediator in lipotoxicity, with Cannabinoid receptor type 1 (CB1) activation promoting lipogenesis and inflammation (211)