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10.1002/pmic.201800311 22 ForresterS

In Raw264.7 macrophages, PARP-1 activation promotes the nuclear translocation of LPS-induced NF-kB, and increased KC activation exacerbates alcohol-induced liver steatosis by increasing hepatic M1 macrophage marker gene expression

doi: 10.1016/j.molcel.2023.12.015 60 EdwardsDNNgwaVMRaybuckALWangSHwangYKimLCet al

Clinical studies concerning the effect of drugs modulating the insulin sensitivity (such as the peroxisome proliferator-activated receptor (PPAR)- agonists) are ongoing in order to provide new potential treatment to improve both the inflammatory status and the CV outcome in RA patients (Table 2)

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doi: 10.1038/sj.onc.1209628 22 MosaddeghzadehNAhmadianMR