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(A Simple Explanation) For fats to be burned for energy, they need to get inside the cell's furnace, the mitochondria

Specifically, B12 is essential for: Fatty acid metabolism: It helps convert fatty acids into succinyl-CoA, which enters the Krebs cycle for ATP production

the synthesis of PEDF in WI-38 fibroblast cells is restricted to the Go stage of the cell cycle in young cells

In addition to a reduction in body mass index, there were also improvements in insulin sensitivity, visceral fat mass, fat-regulating hormones, waist circumference, and markers of inflammation in these studies

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10.1021/bi00364a008 [DOI] [PubMed] [Google Scholar] Matsui T., Nambu S., Ono Y., Goulding C