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Using MRI, a reduction of NP signal intensity and disc height as swell as a higher rate of disc herniation could be documented in 35% of the injected discs compared to 14% in the control group

The kinase mTOR is a major negative regulator of autophagy 57

32 ItohK.ChibaT.TakahashiS.IshiiT.IgarashiK.KatohY.et al (1997)

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The applicant noted that the study is currently in the participant follow-up phase, with the intent for each participant to complete 18 months of follow-up

doi: 10.1016/j.bbadis.2011.08.005