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Then, they switch to a monthly dose

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Hydroxocobalamin (Hydroxy-B12) What it is: A precursor form that your body converts into both methylcobalamin and adenosylcobalamin as needed

The reaction consumes the universal cellular methyl donor SAM and the NAD + salvage precursor nicotinamide, producing a metabolite (1-MNA) that is excreted in urine

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This relieves symptoms of anaemia, including tiredness, fatigue, sore mouth and tongue, numbness and tingling in the arms and legs, memory loss and depression