l-glutamine vs glutathione reduced (L) - Tripeptide of Amino Acids Glycine, Glutamine & Cysteine, Glutamine regulates reactive oxidative stress.

Regulating cellular iron homeostasis after SCI by chelating excess iron ions and modulating iron transport pathways can promote the differentiation of neural stem/progenitor cells into neurons and stimulate the regenerative potential of newborn neurons, accompanied by improvements in axonal reinnervation and myelin regeneration

For example, the open-label mB12/LDFA study selected individuals with poor glutathione and methylation status to potentiate the ability of the treatment to change these parameters (James et al., Like the participants in the mB12/LDFA study, participants in the BH4 study demonstrated some less favorable biomarkers at baseline, but these biomarkers were related to chronic oxidative stress and inflammation

Additional benefits: Improves sleep quality (3-5g before bed) Supports collagen synthesis (skin, joints, tendons) Reduces inflammation (inhibits NF-B signaling) 3

10.1200/jco.2011.29.15_suppl.3025 33 ChaudharyN.NewbyA

N-acetyl L-cysteine (NAC)

10.1155/2013/674751 230 McallumE