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In terms of bacteria and bacterial products, the data strongly support transcellular uptake mechanisms in all but the most extreme situations

doi: 10.1161/CIRCULATIONAHA.106.652859 65

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In contrast, metformin is commonly used during pregnancy for diabetes and polycystic ovary syndrome, and is compatible with breastfeeding

As proxies for liver damage, the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in serum samples using Alanine Aminotransferase Activity Assay Kit (MAK052, Sigma-Aldrich) and Aspartate Aminotransferase Activity Assay Kit (MAK055, Sigma-Aldrich), respectively, according to the manufacturers instructions and adding 3 L and 5 L of serum per well for ALT and AST activity, respectively

[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Samak G, Aggarwal S, Rao RK