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The most commonly documented side effects include nausea (~40% of subjects), flushing, headache, and a transient increase in systolic blood pressure

[13] Early clinical trials showed that the peptide had to be injected about ten times a day due to its short half-life, so the company collaborated with Southern Research in the US to develop a depot formulation that would be injected under the skin, and release the peptide slowly

It belongs to the class of neuroactive peptide hormones targeting melanocortin receptors, particularly MC4R and MC3R

Mechanistyczne ukierunkowanie bada W kontrolowanych warunkach laboratoryjnych Melanotan I jest czsto badany pod ktem aktywnoci receptorw melanokortyny oraz szlakw sygnaowych, w ktrych porednicz peptydy