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A study explored the role of blood-brain barrier (BBB) permeability in lung cancer brain metastasis and found that aspirin administration increased the expression of tight junction proteins (HSP70, ZO-1, and occludin), reducing BBB permeability and potentially inhibiting brain metastasis

The association of Fe 2+ with lipoxygenases (LOX, a dioxygenase containing non-heme iron) can lead to oxygenation of polyunsaturated-fatty-acids (PUFA), such as arachidonic acid present in phospholipids, and trigger lipid peroxidation-induced ferroptosis (Kagan et al., 2017)

like GLP-1, it is secreted after nutrient intake and contributes to glucose-dependent insulin secretion, but it also has distinct effects on adipose tissue and lipid handling that GLP-1 does not replicate

Potential effect of smoking on semen quality through DNA damage and the downregulation of Chk1 in sperm

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