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Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimers disease

Several clinical studies have established beyond any possible doubt that the association is statistically much higher than could be expected by chance ( Table 18-5 )

Koyama K et al

Support for a Healthy Nervous System: Regular B12 supplementation helps maintain nerve health and can prevent complications related to prolonged deficiency

Membranes were probed using antibodies to FoxO1 (1:2500, 18592-1AP, Proteintech, Chicago, IL, USA), SOD2 (1:6000, 66474-1lg, Proteintech, Chicago, IL, USA), NOX4 (1:600, 14347-1-AP, Proteintech, Chicago, IL, USA), and -actin (1:2000, AM10218-400, Abgent) as the primary antibodies