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In transplantation, rituximab was introduced to deplete B cells with the goal of reducing donor-specific antibody (DSA) production ( Unmet Need For Sensitized Patients Because no randomized controlled clinical trial has compared the two main protocols described above, and the study populations and the criteria for transplantation vary, it is difficult to evaluate which protocol is best

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Table 1 Key metabolic pathways, targets, and metabolite alterations involved in RA pathogenesis

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This gives your gut microbiome time to adjust to the new prebiotic fuel