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A total of 616 patients were randomized: 410 patients to the ALIMTA, pembrolizumab, and platinum chemotherapy arm and 206 to the placebo, ALIMTA, and platinum chemotherapy arm

We also compare these results with an analysis of a 500-yr simulation of a coupled climate model with high atmospheric resolution, the Geophysical Fluid Dynamics Laboratory (GFDL) Forecast-oriented Low Ocean Resolution (FLOR) model 31 , for which radiative forcings are held constant at 1990 values