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Imbalance between matrix synthesis and degradation plays a major role in hepatic fibrosis (Shimizu, 2001)

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The right ventricle (RV) and left ventricle plus septum (LV + S) were weighed as previously described [65], and the right-ventricular hypertrophy index was calculated as the weight ratio of RV/(LV + S) and used to describe the degree of right-ventricular hypertrophy