oral melanotic macule on palate Pigmented the mandibular gingiva (a, case 1), affecting the Oral Melanotic Macule: Symptoms and

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MC1R activation promotes eumelanin synthesis, which provides photoprotection

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The initial signs and symptoms often include a lesion that is soft to palpation, usually pigmented, initially asymptomatic, with irregular borders and a color spectrum ranging from dark brown to bluish-black, occasionally presenting variations of gray, purple, and red due to ulcerations, or depigmentation (Figure 5) [39,40]

Using a sunscreen of 15 SPF will help to fade the ephelis and discourage new ones from forming

Not without accepting significant potency loss