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regulations, including the Dietary Supplement Health and Education Act (DSHEA)

32 Another widely used 2-OH substitution is 2-deoxy-2-fluoro (2-F) 69 (Fig

5 , e002762 (2016)

Over 12 months: approximately 1% to 6% of participants across the two cohorts newly met criteria for addiction, as assessed with two validated interview-based measures of moderate-to-severe opioid use disorder based on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria, and approximately 9% and 22% of participants across the two cohorts newly met criteria for prescription opioid abuse and misuse [defined in DRUG ABUSE AND DEPENDENCE], respectively, as measured with a validated self-reported instrument

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Baltimore (Maryland): Williams & Wilkins2007: p