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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI

However, it revealed no statistically significant difference in the change in UPDRS total score between the hydrogen water group and the placebo group at 72 weeks (Yoritaka et al., 2016)

Some medical conditions, including autoimmune disease like shingles (herpes zoster), rheumatoid arthritis or celiac disease, as well as Lyme disease, some cancers, and several other diseases can also cause or increase the risk of nerve damage, also sometimes referred to as peripheral neuropathy

Altered branched-chain alpha-keto acid metabolism is a feature of NAFLD in individuals with severe obesity

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10.1016/j.molcel.2021.07.014 18 BootyL