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Loukas, A., Opdebeeck, J., Croese, J

Reduction of ScGrx7 by GSH is slower than the oxidation by GSSCys (unless Lys105 is replaced, which decelerates the oxidative half-reaction even more than the reductive half-reaction owing to the dual activator function)

It's necessary for making new cells and hormones, but too much of it can be a problem

For those wells to be stimulated with LPS (alone or Al-CPI + LPS), this was added at a final concentration of 10 ng/mL

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In agreement with literature 59 , binding affinities were highest with ssDNA, followed by dsDNA and partial ssRNA and almost no binding to dsRNA, represented by SL1, with no difference between wt and D1467G for any variant RNA and DNA oligonucleotides (Supplementary Fig