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Chen P, Ning L, Qiu P, Mo J, Mei S, Xia C, et al

Extracted ion LC-MS chromatograms (m/z 1183.61184.1) of insulin-SF MH55+ in (A) unmodified insulin (20 g/ml) in human plasma control and (B) human plasma incubated with insulin (20 g/ml) and 50 M SF for 4 h at 37C, showing the appearance of two different insulin-SF conjugates at retention times of 6.46 and 7.08 min

Albumin itself has 17 disulfide bonds (Sugio et al., 1999), meaning the ER in hepatocytes must maintain a high capacity for forming disulfide bonds

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