glutathione for stroke patients Exogenous exerts a therapeutic effect in ischemic rats by interacting with intrastriatal dopamine Plasma glutathione as a risk

Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

Discussion The Trx and Grx systems are both commonly upregulated in tumor cells to compensate for the enhanced ROS production as a result of increased metabolism

While the thiol donors methionine and NAC may increase endogenous antioxidants and antioxidant enzymes, there can be adverse effects associated with their use

Consequently, the ability to salvage and reuse aggregated, unfolded/misfolded proteins and return them to their native folded states at a considerably lower energetic cost [159], allows stress-induced chaperone systems, including heat shock protein 70 (HSP70) [160, 161], to confer living organisms a unique survival advantage during evolution [157]

Sharma C, Jha NK, Meeran MFN, Patil CR, Goyal SN, Ojha S

Emerging roles for non-selenium containing ER-resident glutathione peroxidases in cell signaling and disease