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Clinical Interventions in Aging, 1 (4), 307-308

The adipocyte secretes over 50 cytokines and hormones that both enhance and suppress inflammation, secretes extracellular matrix proteins that impact inflammation, produces and releases toxic lipids that aggravate inflammation, and, more recently, was shown to present antigen to activate CD4+ T cells

Theoretical concerns exist that excessive angiogenesis could promote cancer growth, although this has not been proven in human studies

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They then travel throughout the body to exert their effects

The key is figuring out which approach matches your body and lifestyle