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This effect is attributed to the upregulation of hepatic -catenin, which helps to restore the integrity of tight junctions and normalize the expression of bile transport proteins (OATP2, BSEP, and NTCP1), ultimately inhibiting intrahepatic bile duct dilation, cholestasis, and the progression of fibrosis

It is a complex network, as represented in Figure 1, of interconnected reactions that includes interlaced folate cycles and activated methionine cycles, both of which are required for cellular activity, emphasizing its importance in health maintenance and tissue repair (Suh et al., 2016)

It supports T-cell proliferation and cytokine production, enhancing the immune response

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Phytochemi 47:451457

6,20 Infants with G6PD deficiency and a mutation of uridine diphosphoglucuronate glucuronosyltransferase-1 gene promoter (UDPGT-1) are particularly susceptible to hyperbilirubinemia secondary to decreased liver clearance of bilirubin