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However, the mechanism of KD benefits is still not fully understood, despite some evidence indicating its multiple targets and ability to regulate histone deacetylase, glycolysis, neurotransmitter levels, the function of NLRP3 inflammasome, and oxidative stress

Antibiotics in the tetracycline and quinolone classes, bisphosphonates used for bone health, and thyroid replacement such as levothyroxine are all affected

Furthermore, advances in materials science have made it feasible to incorporate micelles and nanoparticles into contact lenses, which not only boosts patient adherence but also allows for controlled and sustained medication release (241, 242)

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GAPDH was used as an internal housekeeping gene to standardize relative levels of transcription

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