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Kala J, Nelson R, Drudge C, et al

NAC has established medical uses, including treatment of acetaminophen toxicity and use as a mucolytic medication

The nuclear factor-erythroid 2-related factor 2 (Nrf2) involves multiple aspects of cellular and organismal defense against oxidative stress, such as detoxification, regulating cell metabolism, and promoting cell proliferation, which is crucial in the pathological mechanism of various diseases

Fact: Its primarily an antioxidant

The AFB1-Lys adduct has to be liberated from albumin, where the -amino group of lysine reacts with activated AFB1 (reviewed by Kensler et al

Though this ancient gene family has been exhaustively studied in different organisms, still the information available about its sequences and gene organization understates its functional diversity