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Peak years (late teens to early 30s): Testosterone levels reach their lifetime high, typically between ages 18-25

336 Consistent with these findings, MFN2 deficiency impairs mitochondrial fusion and Parkin recruitment, leading to cardiac hypertrophy and heart failure

Studies have shown that oxidative stress and microvascular changes induced by diabetes can damage the integrity of the BTB in diabetic patients, leading to the infiltration of harmful substances into the seminiferous tubules, thereby affecting spermatogenesis [268]