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Oncotarget 7 , 4425244265 (2016)

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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

Greuter T, Vavricka SR

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AOD-9604 AOD9604 (Anti-Obesity Drug 9604) is a synthetic fragment of human growth hormone (HGH) that targets fat metabolism without raising IGF-1