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MATERIALS and METHODS 2.1

Studies suggest that lowering NNMT levels may help counteract some of the mechanisms underlying impaired stem cell function in these disorders

Robert Cox and Sam Jacob of the Histopathology Research Laboratory at Shriners Hospital for Children, Galveston for their support in histological processing and light microscopic analysis of the EWAT tissue samples (grant #84060, PI: Dr

A potentially novel target to treat obesity and type 2 diabetes is nicotinamide-N-methyltransferase (NNMT), a cytosolic enzyme with newly identified roles in cellular metabolism and energy homeostasis