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The combination of dehydroepiandrosterone, transdermal testosterone, and growth hormone as an adjuvant therapy in assisted reproductive technology cycles in patients aged below 40 years with diminished ovarian reserve

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10.3390/antiox10060977 67 KarvelssonS

doi: 10.3201/eid2204.151302 43 WilsonHWAmo-AddaeMKenuEIlesanmiOSAmemeDKSackeySO

First of all, the assessment of treatment efficacy in these studies are limited to the a reduction of senescent cell count as indicated by single markers such as p16 and SA--gal which, as mentioned earlier in this review, may not be an accurate representation of the exact populations targeted by the senolytic CAR-T