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In clinical studies, high circulating TMAO levels have been associated with increased risk of major adverse cardiovascular events 18 , coronary heart disease 19 , cardiometabolic disease 20 , hypertension 21 , and atherosclerosis 22

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[Study on the risk factors of ischemic heart disease in patients with chronic hemodialysis, with special reference to the role of plasma l-carnitine]

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