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204 Symptoms of deficiency include neurological problems like neuropathy, cognitive dysfunction, and depression, as well as anemia, dermatitis, glossitis (inflamed tongue), and weakened immune function

208 Taking high doses of pyridoxine for prolonged periods results in abnormally high circulating pyridoxine levels

Forward Mendelian randomization analysis Firstly, we used Ghodsian et al., GWAS data to perform the forward MR analysis

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This compound represents a significant advancement in neuropharmacology as it was specifically engineered to overcome the limitations of its parent moleculeprimarily poor blood-brain barrier penetration and rapid metabolic degradation

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