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7 Epigenetic regulation strategies Chronic stress and inflammation can lead to epigenetic alterations in genes related to synaptic plasticity and inflammation

5 Reactive oxygen species as oxidizing agents: impact on cysteine proteinases and cellular homeostasis It has long been established that disturbances in reactive oxygen species (ROS) regulation generate highly reactive cellular environments, profoundly influencing intracellular signaling pathways and contributing to oxidative stress

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Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas

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Non-mitochondrial ROS sources in diabetes Regardless of whether excessive ROS formation is the primary initiator or accompanying factor in the pathogenesis of diabetes mellitus, oxidative stress plays a key role in the organ complications such as cardiovascular problems, neurological problems (stroke), diabetic retinopathy, nephropathy, and neuropathy