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Another TKI, gefitinib (ZD1839, Iressa), which targets the epidermal growth factor receptor (EGFR), has been shown to restrict M.tb replication in both macrophages as well as in the lungs of M.tb -infected mice by promoting the host autophagy pathway through the inhibition of the p38 MAPK signaling pathway activated by EGFR [10]

Additionally, medicinal mushrooms, including Ganoderma lucidum and Panus conchatus , are known as EGT producers (Kalaras et al

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In 2018, Dieterich et al

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics