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When 5-amino-1MQ increases cellular NAD+ levels, it enhances mitochondrial function, the powerhouses responsible for converting nutrients into usable cellular energy

They help to regenerate, nourish and protect the nerves in the long-term, along with proper diet and exercise

Nat Med (2015) 21(8):88794

NNMT sits between NAD+ metabolism and one-carbon methylation metabolism, pathways that support redox reactions, DNA repair, and transcriptional regulation

While more human data is needed, its mechanism aligns with many principles of functional and longevity medicine namely, supporting mitochondria, reducing inflammation, and improving insulin sensitivity