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Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase

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Homge M, Haimi J, Pinkel D, Gray J, Chaganti R, O'Reilly R, Kernan N, Andreeff M

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The pentapeptide dissolves cleanly in aqueous buffer at neutral pH, with no need for DMSO or other organic co-solvents at typical working concentrations

Therefore, there is an urgent need for a novel diagnostic technique that enhances specificity, sensitivity, while being simple and affordable and ideal in a resource limited setting