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Multiple abnormalities at various stages of organogenesis in RAR double mutants

doi: 10.1073/pnas.1918540117 120

Brill KT, Weltman AL, Gentili A, et al

4,26 PLP deficiency has also been reported to be caused by displacement of pyridoxal phosphate from circulating albumin by acetaldehyde (an alcohol metabolite), which increases urinary excretion

Attributing to the safe, fast and reliable practicability of EPT testing, a clinical trial enrolled 52 participants with RP to treat with either 30 min once a week of transcorneal ES for 52 weeks or sham (NCT01837901)