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The assessment of plasma TMAO profiles after the exposure to a precursor, such as in an OCC, is essential to capture the effect of the polyphenols on the magnitude and timing of TMAO exposure rather than fasting TMAO concentrations alone

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However, it is worth noting that this study was conducted without a placebo control group, which limits its ability to draw firm conclusions

The rest fragment ions in extracted spectra were first matched with the residues of endogenous compounds, usually amino acids, and then utilized to reconstitute entire structures of thiols

Waiting 45-60 minutes is even better

PLS-DA pre-treatment CER = 0.23