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Clinically, PCOS patients typically present with ovarian dysfunction and dysregulated glucose and lipid metabolism

An unbalanced redox state, including impaired mitochondrial function, dysregulated lipid metabolism, and iron-induced oxidative stress, generates a pro-oxidative microenvironment, which negatively impacts oocyte quality and sperm and embryo viability

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However, the underlying mechanisms of VPA-caused hepatotoxicity remain unclear

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This highlights the need for clinicians to be aware of both general anticoagulant properties and specific drugdrug interaction alerts