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Commun Biol 9 , 970 (2026)

In fact, since 1973, when the first report of CPTII deficiency was published by DiMauro and DiMauro (1973), patients have been advised to maintain a carbohydrates-rich diet (CHORD), reducing dietary fat, and to restrain from physical activities (rest) to prevent rhabdomyolysis or other unfavorable muscle conditions (Joshi and Zierz, 2020)