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Neurons almost exclusively express the MCT2 isoform, which possesses a high affinity for BHB released from endothelial cells and astrocytes

TET enzymes, together with Jumonji-C (JmjC) domain-containing demethylases that regulate chromatin structure by altering the methylation process, represent two key categories of epigenetic regulators that involve iron (Farida et al., 2023[133])