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Here, we propose ZIL as a potent, multifunctional and biocompatible solvent for use in the life sciences, which we also confirmed to be applicable to general plastic tools in biological and biochemical laboratories (Supplementary Fig

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Since ER-mitochondria Ca 2+ transfer is essential for cancer cell bioenergetics (106), metastasis (107), and chemoresistance (108), the anti-cancer effects of crotamine may rely on the disruption of ER-mitochondria axis and activation of Ca 2+ -dependent cytosolic proteases