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Many people attribute such symptoms to stress or the hectic pace of everyday life

Osteoarthritis pain: nociceptive or neuropathic

ACTION Strong antioxidant and support for protection against oxidative stress (glutathione) Lightens discolorations and evens out skin tone (niacinamide) Smoothes fine wrinkles and supports firmness (adenosine + peptides) Intensively moisturizes and improves elasticity (HA complex, panthenol) EFFECT Visibly brighter, more even and radiant complexion Soft, moisture-rich skin with a glow effect Less visible fine lines and a fresher appearance ACTIVE INGREDIENTS Glutathione 5% antioxidant, anti-age and brightening support Niacinamide 5% reduces spots, regulates sebum, strengthens the barrier Adenosine skin smoothing and elasticity Panthenol + HA complex (multiple forms) deep hydration and plump Peptides (Palmitoyl Tripeptide-5, Acetyl Octapeptide-3, Acetyl Dipeptide-1) anti-wrinkle support HOW TO USE Apply a small amount to cleansed face (and neck), pat until absorbed, then apply cream

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Also, pre-treatment with clinically relevant agents such as ATRA and Panobinostat could be used to enhance CD38 expression

J Neurol, 2024