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Although previous studies have used nano-fluorescent probes to detect the cellular delivery efficiency of oligonucleotide molecules, 403,457,575 more pharmacokinetic data on biodistribution, immune compatibility, and toxicity are needed for clinical translation and practical therapeutic application of these systems

The median time to reach therapeutic levels across all age groups was approximately 3 days, with an interquartile range of 2 days to 6 days

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Emerging concepts in Periprosthetic joint infection research: the human microbiome