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In this study, we found that in vitro exposure to IL-1 was sufficient to induce pT H 17 cells, driving an increase in CD38-expressing cells, whereas in vivo targeting CD38 consistently decreased cortical IL-1 in the AD brain, suggesting that CD38 treatment could lead to IL-1-mediated modulation of T H 17 cell pathogenicity

Several characteristic metabolic mechanisms involving glucose and amino acids (AAs) in cancer cells have been revealed, and new insights continue to emerge (2)

Patients curiosity about diet and lack of precise recommendations compel them to seek information from the Internet and other non-medical sources [10,11]

The measure of bacterial metabolites such as butyrate in serum or feces is another approach, due to its role in enhancing colonic barrier function

Cisplatin is a commonly used drug for treating osteosarcoma, but osteosarcoma cells can develop resistance to it, which reduces its therapeutic effect (190)

Neuroreport 10(14):29652969 Galasko D (2003) Insulin and Alzheimers disease: an amyloid connection