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256 In addition, ethanol could activate kinase CK2 to phosphorylate MAT1 at Ser114, promote its interaction with PIN1 isomerase, inhibit MAT1 localization in mitochondria, and promote ethanol-induced mitochondrial dysfunction and fat accumulation

Cardiovascular diseases Cardiovascular diseases (CVD) have multifactorial origins and according to WHO are the major cause of death worldwide (Benjamin et al