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Data from scRNA-seq and Western blot analyses of kidney tissues from mice with oxalate-induced AKI, along with observations of primary PTECs treated with CaOX, either alone or co-incubated with ferroptosis-specific inhibitors, demonstrated the occurrence of ferroptosis in renal tubular cells within the oxalate-induced AKI model

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Metformin, macrophage dysfunction and atherosclerosis

As a marker for Candida colonization, we measured citramalic acid, which has been shown to be produced by various species of yeast

10 l from each well was acquired on a BD FACSCelesta, then the median fluorescence intensity (MFI) of the PE-positive cells was calculated for each well using FlowJo v10.8 Software (BD Life Sciences)

Our group is currently conducting a randomized pilot study called PEGASUS (NCT05132244) at the BC Cancer Agency in Vancouver, Canada, to investigate the interplay between diabetes and PDAC by closely monitoring glucose levels in PDAC patients and associating its effect on clinical outcome (118)