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HU was used at a final concentration of 15 mM for 3.5 h at 30 C in rich medium

doi: 10.1038/srep09222

The increase in lipid content is in agreement with the results reported by Amira et al

Chronic hyperglycemia impairs wound healing by decreasing leukocyte function and reducing peripheral perfusion

In the mevalonate pathway, the enzyme 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase, which converts HMG-CoA into mevalonate, is common to the biosynthetic pathways of both coenzyme Q 10 and cholesterol and is inhibited by statins (cholesterol-lowering drugs

The activation of NADPH oxidases, which results in ROS production, is involved in a wide array of functions, including host defense, cellular signaling, gene expression regulation, cell differentiation, metabolic processes, post-translational protein modifications, stress responses, and the maintenance of tissue homeostasis