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Clock gene expression was reduced by a factor of 1.8 relative to the placebo

Vitamins A, C and E have also demonstrated some importance in the prognosis of patients with COVID-19, since their deficiencies have been reported, especially in the most severe COVID-19 patients (228)

is supported by Cancer Research UK, grant number C42109/A26982

In addition, ROS are also produced as by-products of several cellular enzymes, such as nicotinamide adenine dinucleotide phosphate oxidases (NOXs), xanthine oxidoreductase (XOR), and lipoxygenases (LOXs)

The authors further suggest that suppression of stress pathways might be an effective therapy for AD (Zhang and Rissman, 2017)

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